Selank

🧠 Selank Peptide: Comprehensive Guide for Laboratory Research

Overview of Selank in Research

Selank is a synthetic neuropeptide derived from the naturally occurring peptide Tuftsin. It is widely used in preclinical research for its neuroprotective, anxiolytic, and cognitive-modulating effects. Selank influences neurotransmitter systems, including serotonin and GABA, while demonstrating high molecular stability, making it a reliable compound for in vitro studies.

This guide evaluates Selank peptide products based on purity, synthesis quality, documentation, and stability, providing a reference for laboratories and academic research institutions.

⚠️ Disclaimer: Selank peptides are intended strictly for laboratory research and are not approved for human or veterinary use.

What Is Selank?

Selank is a heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from Tuftsin, with an additional Pro-Gly-Pro sequence to enhance its stability and prolong activity. Preclinical studies indicate that Selank can:

• Modulate GABAergic and serotonergic neurotransmission
• Exhibit anxiolytic and nootropic effects in vitro
• Influence immune responses and reduce inflammatory signaling
• Provide neuroprotective effects under stress conditions

Researchers utilize Selank to explore neurochemical modulation, stress responses, and cognitive function.

Selank Peptide Product Ranking

Key factors for selecting a Selank peptide include purity, verification, synthesis quality, storage form, and documentation. The following table provides a comparative overview of research-grade Selank peptides:

Note: Product names are generic representations; always verify Certificate of Analysis (CoA) and purity before purchasing.

Key Attributes of High-Quality Selank

1. Purity and Verification
   • Research-grade Selank should have ≥95% purity, confirmed via HPLC and mass spectrometry.
   • High purity ensures reproducible results in neurochemical and receptor-binding assays.
2. Synthesis and Stability
   • Produced via solid-phase peptide synthesis (SPPS) and purified with HPLC.
   • Lyophilized powder enhances stability during storage and transport.

   Storage Guidelines:

   • Lyophilized: −20°C, protected from light and moisture
   • Reconstituted: aliquots stored at −80°C; avoid repeated freeze-thaw cycles
3. Documentation and Traceability
   • Supplier should provide CoA, HPLC/MS data, batch number, synthesis date, and research-use-only certification.
4. Molecular Stability
   • Selank’s structure resists enzymatic degradation, suitable for long-term in vitro experiments.

Applications in Research

Selank’s neuroactive and immunomodulatory properties make it relevant for:

• Neurotransmitter Studies: Investigating GABAergic and serotonergic pathways
• Cognitive and Stress Research: Evaluating effects on learning, memory, and cognitive performance under stress
• Immunomodulatory Research: Studying influence on cytokine balance and immune-neural signaling
• Comparative Studies: Analyzing structure-function relationships in synthetic neuropeptides alongside analogs like Semax

Advantages of Top-Tier Selank

• High purity (≥98%) ensures minimal contaminants and accurate results
• Consistent batch quality supports reproducibility
• Stable lyophilized form extends shelf life and simplifies storage
• Verified analytical data (CoA, HPLC, MS) enhances research credibility
• Maintains neuropeptide activity for CNS and immune system studies

Handling and Storage

• Store lyophilized Selank at −20°C in a dry, airtight container
• Reconstitute under sterile conditions and divide into aliquots
• Avoid repeated freeze-thaw cycles
• Label with batch and reconstitution date
• Follow institutional safety protocols

Frequently Asked Questions (FAQ)

1. Mechanism of Action:
   • Modulates serotonin and GABA pathways, affecting anxiety, cognition, and emotional regulation
2. Purity Standards:
   • Research-grade Selank typically ranges 95–99%, verified by HPLC and MS
3. Applications:
   • Neurochemical, cognitive, immunological, and stress-response studies
4. Human Use Approval:
   • Selank is not approved for human or veterinary use; laboratory research only
5. Storage:
   • Lyophilized: −20°C; reconstituted: −80°C, protected from light and moisture

Conclusion

Selank peptide is a widely studied synthetic neuropeptide valued for its cognitive, anxiolytic, and immunomodulatory properties. Its stability and reproducibility make it an ideal choice for controlled in vitro research.

When selecting Selank for laboratory use, prioritize:

• Verified purity (≥98%)
• HPLC/MS confirmation
• Comprehensive CoA and documentation
• Stable lyophilized formulation

High-quality Selank ensures reliable experimental outcomes and advances the understanding of neuroactive peptide mechanisms.

⚠️ For laboratory research only. Not for human or veterinary use.