Price range: $45.00 through $300.00

Product Information:

Name: Melanotan II; MT2
CAS No.: 121062-08-6
Peptide Sequence: Ac-Nle-Asp(1)-His-DPhe-Arg-Trp-Lys(1)-NH2
Molecular Formula: C50H69N15O9
Molecular Weight: 1024.18
Appearance: White Lyophilized powder

 

🌞 Melanotan II (MT-2) Peptide – Synthetic α-MSH Analog for Research

🧬 Overview

Melanotan II (MT-2) is a synthetic cyclic peptide and analog of the naturally occurring α-Melanocyte Stimulating Hormone (α-MSH). Widely used in laboratory research, MT-2 is a versatile tool for studying melanocortin receptor signaling, melanin production, photoprotection, and neuroendocrine pathways.

Designed for laboratory investigations, Melanotan II supports research in dermatology, cellular signaling, energy metabolism, and neurobiology. This peptide is produced under strict GMP-like conditions and verified at ≥98% purity for reproducible experimental results.


⚙️ Molecular Profile

Property Specification
Name Melanotan II (MT-2)
Synonyms α-MSH analog, Melanocortin II peptide
CAS Number 121062-08-6
Molecular Formula C₅₀H₆₉N₁₅O₉
Molecular Weight 1024.18 g/mol
Sequence Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH₂
Purity ≥98% (HPLC verified)
Form Lyophilized powder
Solubility Sterile water or PBS
Storage −20°C, dry and protected from light
Shelf Life 24 months (unreconstituted)

🔬 Mechanism of Action

Melanotan II functions as a non-selective agonist of melanocortin receptors (MC1R–MC5R). Key effects in research models include:

  • Pigmentation & Photoprotection: Activation of MC1R stimulates melanin synthesis, providing natural photoprotective effects in skin cells.
  • Neuroendocrine & Energy Regulation: Engagement of MC3R and MC4R enables studies of appetite, metabolism, and hormonal signaling.
  • Inflammatory Modulation: MT-2 is used to explore melanocortin pathways involved in oxidative stress and immune response.

Its multi-receptor activity allows researchers to investigate cross-talk between pigmentation, metabolism, and neuroendocrine processes.


🌿 Research Applications

  1. Melanogenesis & Pigmentation Studies – Modeling melanin production and tanning mechanisms in vitro and in vivo.
  2. Photoprotection & UV Response – Studying cellular defense against UV-induced damage.
  3. Melanocortin Receptor Signaling – Exploring receptor interactions, signal transduction, and neuroendocrine pathways.
  4. Anti-Inflammatory Research – Investigating cytokine modulation and oxidative stress.
  5. Peptide Therapeutics Development – Serving as a model peptide for receptor-based drug research.

🧪 Quality & Manufacturing

  • Synthesized via solid-phase peptide synthesis (SPPS).
  • Purity verified by HPLC and molecular identity confirmed with mass spectrometry.
  • Manufactured in GMP-comparable conditions and delivered as lyophilized powder.
  • Each batch includes a Certificate of Analysis (COA) verifying sequence, purity, and endotoxin levels.

⚠️ Safety & Handling

  • For Research Use Only: Not approved for human or animal use.
  • Storage: Keep lyophilized peptide at −20°C, protected from light and moisture.
  • Reconstitution: Use sterile water or PBS; refrigerate reconstituted peptide and avoid repeated freeze–thaw cycles.

🌍 Why Choose [Your Brand Name]?

  • ≥98% HPLC & MS-verified purity
  • GMP-grade manufacturing
  • COA included with every batch
  • Secure, vacuum-sealed packaging
  • Worldwide fast shipping
  • Dedicated research support

🧾 Product Summary

  • Name: Melanotan II (MT-2)
  • Type: Synthetic α-MSH analog
  • Form: Lyophilized powder
  • Purity: ≥98%
  • Intended Use: Research only
  • Storage: −20°C, dark and dry environment

❓ FAQs

Q1. What is Melanotan II peptide?
A: A synthetic α-MSH analog used in laboratory research on pigmentation, receptor signaling, and photoprotection.

Q2. How pure is Melanotan II?
A: ≥98% purity, verified through HPLC and mass spectrometry.

Q3. Can MT-2 be used in humans?
A: No. MT-2 is strictly for scientific research.

Q4. What are common research applications?
A: Melanin production, UV protection, melanocortin receptor signaling, and peptide pharmacology studies.

Q5. How should it be stored?
A: Keep lyophilized peptide at −20°C in a dark, dry place; reconstituted peptide should be refrigerated.