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Name: Melanotan I; MT1
CAS No.: 75921-69-6
Peptide Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Molecular Formula: C78H111N21O19
Molecular Weight: 1646.9
Appearance: White Lyophilized powder
Introduction
Melanotan I, also referred to as α-Melanocyte Stimulating Hormone (α-MSH) analog or Afamelanotide, is a synthetic peptide widely used in laboratory research to investigate melanogenesis, skin pigmentation, and photoprotection pathways. It serves as a selective agonist of the melanocortin 1 receptor (MC1R), making it a valuable tool for studies in dermatology, cell signaling, and peptide pharmacology.
Research-Grade Specifications
| Property | Specification |
|---|---|
| Name | Melanotan I |
| Synonyms | Afamelanotide, α-MSH analog, NDP-MSH |
| Molecular Formula | C78H111N21O19 |
| Molecular Weight | ~1646.9 g/mol |
| Sequence | Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂ |
| Purity | ≥ 98% (HPLC verified) |
| Appearance | White lyophilized powder |
| Storage | −20°C, protected from light |
| Solubility | Sterile water or PBS |
Scientific Background
Melanotan I mimics the action of α-MSH, promoting melanin synthesis in skin cells through MC1R activation. In laboratory research, it is used to explore:
Usage Guidelines
Why Choose This Research Peptide?
Summary
Melanotan I peptide is an essential research tool for laboratories studying melanogenesis, photoprotection, and MC1R signaling. Its high purity and lab-verified quality make it ideal for reproducible experimental results in molecular biology, dermatological research, and peptide signaling studies.

















